![]() As long as a medication conforms to one of these monographs, it can be marketed as either one. In this case, DPH has two monographs, one stating that it can be taken at 25mg or 50mg for allergies, and one stating that it can be taken at 50mg as a sleep aid. The FDA reviews OTC drugs through drug monographs, which are statements about the acceptable ingredients, dosage, and usage of a certain drug. So, why is one drug marketed as an antihistamine and one marketed as a sleep aid? It comes down to how over-the-counter drugs are regulated by the FDA. They recommend you only take ZzzQuil if you know you’ll have enough time to get a full night’s rest, however much that usually is for you. On the ZzzQuil site, the manufacturers note that there are “many factors” that could influence how well rested you feel the next morning, including the time you take ZzzQuil. Benadryl doesn’t contain any such warning, even though experts agree that it’s not good to take it over the long term.īut taking ZzzQuil to help you sleep could, theoretically, come with the same potential side effects of taking Benadryl, like next-day sleepiness. When reached for comment, Procter & Gamble, the makers of ZzzQuil, emphasized these instructions. ZzzQuil is indicated for “the relief of occasional sleeplessness,” and the warning label advises consumers to stop use and consult a doctor if they’re still having trouble sleeping after two weeks. (Except for one that only has the active ingredient melatonin.) Therefore, these ZzzQuil products essentially work in the same way as Benadryl, but they’re marketed specifically to help you get sleep-in the short-term, that is. ZzzQuil products, on the other hand, have the exact same active ingredient. In fact, Johnson & Johnson, the makers of Benadryl, declined to comment on this subject as it discusses an off-label use. But only one is indicated for helping you fall asleep.Īlthough Benadryl lists “marked drowsiness” as a potential side effect, it is not indicated for sleep on its packaging. Here’s something you may not know: DPH is the sole active ingredient in both Benadryl and ZzzQuil. If you take a medication with DPH for extended periods, you might get into a vicious cycle of needing more yet feeling even sleepier throughout the day. Higher doses mean a greater risk of side effects, like next-morning sleepiness. This means you will need to take an increasingly higher dose to achieve the same effect. ![]() ![]() “The body adapts to them.” With daily use, you may build up a tolerance in about two weeks, he says, though the specific timeline here can vary from person to person. "It's typically intended to be taken for short periods of time, such as several weeks or months, but not continuously forever (unless you're working with a doctor)," says Axe.You can also build up a tolerance to DPH fairly quickly. According to the National Sleep Foundation, a low dose is generally considered 0.5 mg and 5mg is on the higher side.įor those who do take melatonin daily, Axe says it doesn't hurt to take a break from it every now and then. ![]() "Try taking a low dose to start, taking it about 60 minutes before sleep and skipping continuous release melatonin if this seems to apply to you," he advises. "After you take melatonin it starts working within about an hour and lasts for about 5 hours in your body, so taking it in the middle of the night isn't the best idea if you want to wake up with energy," he explains. To start, he says to avoid taking it in the middle of the night. If you experience side effects like next-day drowsiness when you take melatonin, does that mean you should never take it? According to Axe, you might be able to try a few adjustments first. $9 at Amazon Ways to prevent a melatonin hangover Taking melatonin is thought to improve sleep because it can help your body produce more of the hormone. Melatonin is a hormone that's produced naturally in the body, and it helps tell you when to sleep and when to wake up. Why does melatonin make me feel hungover? CBN is a type of cannabinoid that is being used in more sleep supplements since it's the most sedative compound found in cannabis, according to Sandland Sleep.
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